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Use of Tissue-Specific MicroRNA to Control Pathology of Wild-Type Adenovirus without Attenuation of Its Ability to Kill Cancer Cells
Replicating viruses have broad applications in biomedicine, notably in cancer virotherapy and in the design of attenuated vaccines; however, uncontrolled virus replication in vulnerable tissues can give pathology and often restricts the use of potent strains. Increased knowledge of tissue-selective...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
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Public Library of Science
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678247/ https://ncbi.nlm.nih.gov/pubmed/19461878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000440 |
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