A ceramide-1-phosphate analogue, PCERA-1, simultaneously suppresses tumour necrosis factor-α and induces interleukin-10 production in activated macrophages

Tight regulation of the production of the key pro-inflammatory cytokine tumour necrosis factor-α (TNF-α) is essential for the prevention of chronic inflammatory diseases. In vivo administration of a synthetic phospholipid, named hereafter phospho-ceramide analogue-1 (PCERA-1), was previously found t...

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Detalhes bibliográficos
Main Authors: Goldsmith, Meir, Avni, Dorit, Levy-Rimler, Galit, Mashiach, Roi, Ernst, Orna, Levi, Maya, Webb, Bill, Meijler, Michael M, Gray, Nathanael S, Rosen, Hugh, Zor, Tsaffrir
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678186/
https://ncbi.nlm.nih.gov/pubmed/18793216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02928.x
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