A Substrate Trapping Mutant Form of the Tyrosine Phosphatase STEP Prevents Amphetamine-induced Stereotypies and Long-term Potentiation in the Striatum

BACKGROUND: Chronic, intermittent exposure to psychostimulants results in striatal neuroadaptations leading to an increase in an array of behavioral responses on subsequent challenge days. STEP, a brain-specific STriatal Enriched tyrosine Phosphatase, regulates synaptic strengthening by dephosphoryl...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tashev, Roman, Moura, Paula J., Venkitaramani, Deepa V., Prosperetti, Chiara, Centonze, Diego, Paul, Surojit, Lombroso, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678172/
https://ncbi.nlm.nih.gov/pubmed/19026408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.10.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados