Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study

BACKGROUND: This study was designed to investigate the efficacy and safety of the epidermal growth factor receptor (EGFR) inhibitor cetuximab combined with irinotecan, folinic acid (FA) and two different doses of infusional 5-fluorouracil (5-FU) in the first-line treatment of EGFR-detectable metasta...

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Hauptverfasser: Raoul, Jean-Luc, Van Laethem, Jean-Luc, Peeters, Marc, Brezault, Catherine, Husseini, Fares, Cals, Laurent, Nippgen, Johannes, Loos, Anja-Helena, Rougier, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678147/
https://ncbi.nlm.nih.gov/pubmed/19366444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-112
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