Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase I/II study

BACKGROUND: This study was designed to investigate the efficacy and safety of the epidermal growth factor receptor (EGFR) inhibitor cetuximab combined with irinotecan, folinic acid (FA) and two different doses of infusional 5-fluorouracil (5-FU) in the first-line treatment of EGFR-detectable metasta...

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Главные авторы: Raoul, Jean-Luc, Van Laethem, Jean-Luc, Peeters, Marc, Brezault, Catherine, Husseini, Fares, Cals, Laurent, Nippgen, Johannes, Loos, Anja-Helena, Rougier, Philippe
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678147/
https://ncbi.nlm.nih.gov/pubmed/19366444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-112
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