Function, Activity, and Membrane Targeting of Cytosolic Phospholipase A(2)ζ in Mouse Lung Fibroblasts

Group IVA cytosolic phospholipase A(2) (cPLA(2)α) initiates eicosanoid production; however, this pathway is not completely ablated in cPLA(2)α(−/−) lung fibroblasts stimulated with A23187 or serum. cPLA(2)α(+/+) fibroblasts preferentially released arachidonic acid, but A23187-stimulated cPLA(2)α(−/−...

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Hauptverfasser: Ghosh, Moumita, Loper, Robyn, Ghomashchi, Farideh, Tucker, Dawn E., Bonventre, Joseph V., Gelb, Michael H., Leslie, Christina C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678067/
https://ncbi.nlm.nih.gov/pubmed/17293613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M608458200
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