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Polyanion-Induced Self Association of Complement Factor H

Factor H is the primary soluble regulator of activation of the alternative pathway of complement. It prevents activation of complement on host cells and tissues upon association with C3b and surface polyanions such as sialic acids, heparin and other glycosaminoglycans. Here we show that interaction...

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Autori principali: Pangburn, Michael K., Rawal, Nenoo, Cortes, Claudio, Alam, M. Nurul, Ferreira, Viviana P., Atkinson, Mark A. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677913/
https://ncbi.nlm.nih.gov/pubmed/19124749
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