The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription

Glis3 is a member of the Krüppel-like family of transcription factors and is highly expressed in islet β cells. Mutations in GLIS3 cause the syndrome of neonatal diabetes and congenital hypothyroidism (NDH). Our aim was to examine the role of Glis3 in β cells, specifically with regard to regulation...

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Hlavní autoři: Yang, Yisheng, Chang, Benny Hung-Junn, Samson, Susan L., Li, Ming V., Chan, Lawrence
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677877/
https://ncbi.nlm.nih.gov/pubmed/19264802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp122
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