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An intranasal heat shock protein based vaccination strategy confers protection against mucosal challenge with herpes simplex virus

Herpes simplex virus-1 (HSV-1) represents a significant obstacle for vaccine designers, despite decades of investigation. The virus primarily infects the host at vulnerable mucosal surfaces that progresses to lesion development, latency in nervous tissue, and possible reactivation. Therefore, protec...

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Bibliografske podrobnosti
Main Authors: Pack, Christopher D., Gierynska, Malgorzata, Rouse, Barry T.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677698/
https://ncbi.nlm.nih.gov/pubmed/18382144
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