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Regulation of ErbB2 Receptor Status by the Proteasomal DUB POH1

Understanding the factors, which control ErbB2 and EGF receptor (EGFR) status in cells is likely to inform future therapeutic approaches directed at these potent oncogenes. ErbB2 is resistant to stimulus-induced degradation and high levels of over-expression can inhibit EGF receptor down-regulation....

詳細記述

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書誌詳細
主要な著者: Liu, Han, Buus, Richard, Clague, Michael J., Urbé, Sylvie
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677670/
https://ncbi.nlm.nih.gov/pubmed/19436748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005544
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