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Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging
Bioorthogonal tetrazine cycloadditions have been applied to live cell labeling. Tetrazines react irreversibly with the strained dienophile norbornene forming dihydropyrazine products and dinitrogen. The reaction is high yielding, selective, and fast in aqueous media. Her2/neu receptors on live human...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677645/ https://ncbi.nlm.nih.gov/pubmed/19053305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc8004446 |
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