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Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

Bioorthogonal tetrazine cycloadditions have been applied to live cell labeling. Tetrazines react irreversibly with the strained dienophile norbornene forming dihydropyrazine products and dinitrogen. The reaction is high yielding, selective, and fast in aqueous media. Her2/neu receptors on live human...

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書誌詳細
主要な著者: Devaraj, Neal K., Weissleder, Ralph, Hilderbrand, Scott A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677645/
https://ncbi.nlm.nih.gov/pubmed/19053305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc8004446
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