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Development of Spin-Labeled Pargyline Analogues as Specific Inhibitors of Human Monoamine Oxidases A and B

Three TEMPO conjugated pargyline analogues (ParSL-1, ParSL-2 and ParSL-3) have been synthesized and their inhibitory properties tested for the two human monoamine oxidase isoforms (hMAOA and hMAOB). The three analogues differ in flexibility and substituent positions (para or meta) of the linkers con...

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Bibliographic Details
Main Authors: Upadhyay, Anup K., Edmondson, Dale E.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677634/
https://ncbi.nlm.nih.gov/pubmed/19296688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002106
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