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In vivo analysis of the 3′ untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone

Large sections of the 3′ untranslated region (UTR) of hepatitis C virus (HCV) were deleted from an infectious cDNA clone, and the RNA transcripts from seven deletion mutants were tested sequentially for infectivity in a chimpanzee. Mutants lacking all or part of the 3′ terminal conserved region or t...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yanagi, Masayuki, St. Claire, Marisa, Emerson, Suzanne U., Purcell, Robert H., Bukh, Jens
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2291
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