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Defective Peripheral Nerve Development Is Linked to Abnormal Architecture and Metabolic Activity of Adipose Tissue in Nscl-2 Mutant Mice

BACKGROUND: In mammals the interplay between the peripheral nervous system (PNS) and adipose tissue is widely unexplored. We have employed mice, which develop an adult onset of obesity due to the lack the neuronal specific transcription factor Nscl-2 to investigate the interplay between the nervous...

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Main Authors: Ruschke, Karen, Ebelt, Henning, Klöting, Nora, Boettger, Thomas, Raum, Kay, Blüher, Matthias, Braun, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677458/
https://ncbi.nlm.nih.gov/pubmed/19436734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005516
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