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MMPs as therapeutic targets – still a viable option?
Matrix metalloproteinases (MMPs) appear to be ideal drug targets – they are disease-associated, extracellular enzymes with a dependence on zinc for activity. This apparently straightforward target, however, is much more complex than initially realized. Although disease associated, the roles for part...
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2007
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677300/ https://ncbi.nlm.nih.gov/pubmed/17693104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2007.06.006 |
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