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Induction of IL-17(+) T cell trafficking and development by IFN-γ: Mechanism and pathological relevance in psoriasis
Th1 and Th17 T cells are often co-localized in pathological environments, yet Th1 derived-interferon (IFN)-γ inhibits Th17 cell development in vitro. We explored the physiologic basis of this paradox in humans. Here we demonstrate increased numbers of CD4(+)IL-17(+) and CD8(+)IL-17(+) T cells in ski...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677162/ https://ncbi.nlm.nih.gov/pubmed/18802076 |
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