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The Oak Ridge Polycystic Kidney Mouse: Modeling Ciliopathies of Mice and Men
The Oak Ridge Polycystic Kidney (ORPK) mouse was described nearly 14 years ago as a model for human recessive Polycystic Kidney Disease. The ORPK mouse arose through integration of a transgene into an intron of the ift88 gene resulting in a hypomorphic allele (Ift88(Tg737Rpw)). The Ift88(Tg737Rpw) m...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677030/ https://ncbi.nlm.nih.gov/pubmed/18366137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21515 |
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