MRI correlates of neurofibrillary tangle pathology at autopsy: A voxel-based morphometry study

BACKGROUND: Neurofibrillary tangles (NFTs), composed of hyperphosphorylated tau proteins, are one of the pathologic hallmarks of Alzheimer disease (AD). We aimed to determine whether patterns of gray matter atrophy from antemortem MRI correlate with Braak staging of NFT pathology. METHODS: Eighty-th...

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主要な著者: Whitwell, J L., Josephs, K A., Murray, M E., Kantarci, K, Przybelski, S A., Weigand, S D., Vemuri, P, Senjem, M L., Parisi, J E., Knopman, D S., Boeve, B F., Petersen, R C., Dickson, D W., Jack, C R.
フォーマット: Artigo
言語:Inglês
出版事項: American Academy of Neurology 2008
主題:
Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676950/
https://ncbi.nlm.nih.gov/pubmed/18765650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000324924.91351.7d
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