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Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma

Cholangiocarcinoma is an intractable cancer, with no effective therapy other than surgical resection. Elevated vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) expressions are associated with the progression of cholangiocarcinoma. We therefore examined whether in...

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Bibliografiske detaljer
Main Authors: Yoshikawa, D, Ojima, H, Kokubu, A, Ochiya, T, Kasai, S, Hirohashi, S, Shibata, T
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676540/
https://ncbi.nlm.nih.gov/pubmed/19319137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604988
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