Terreic acid, a quinone epoxide inhibitor of Bruton’s tyrosine kinase

Bruton’s tyrosine kinase (Btk) plays pivotal roles in mast cell activation as well as in B cell development. Btk mutations lead to severe impairments in proinflammatory cytokine production induced by cross-linking of high-affinity IgE receptor on mast cells. By using an in vitro assay to measure the...

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Bibliografiska uppgifter
Huvudupphovsmän: Kawakami, Yuko, Hartman, Stephen E., Kinoshita, Eiji, Suzuki, Hidefumi, Kitaura, Jiro, Yao, Libo, Inagaki, Naoki, Franco, Alessandra, Hata, Daisuke, Maeda-Yamamoto, Mari, Fukamachi, Hiromi, Nagai, Hiroichi, Kawakami, Toshiaki
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC26765/
https://ncbi.nlm.nih.gov/pubmed/10051623
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