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Structural insights into chondroitin sulphate A binding Duffy-binding-like domains from Plasmodium falciparum: implications for intervention strategies against placental malaria

BACKGROUND: Placental malaria is typified by selective clustering of Plasmodium falciparum in the intervillous blood spaces of the placenta. Sequestration of malaria parasite in the human placenta is mediated by interactions between chondroitin sulphate A (CSA) on the syncytiotrophoblasts and protei...

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Main Authors: Gill, Jasmita, Chitnis, Chetan E, Sharma, Amit
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676308/
https://ncbi.nlm.nih.gov/pubmed/19374733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-67
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