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Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people
BACKGROUND: Simvastatin reduces cardiovascular mortality and morbidity but, as with other HMG-CoA reductase inhibitors, can cause significant muscle toxicity and has been associated with elevations of liver transaminases. METHODS: Muscle and liver adverse effects of simvastatin 40 mg daily were eval...
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| Format: | Artigo |
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| Jezik: | Inglês |
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BioMed Central
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676245/ https://ncbi.nlm.nih.gov/pubmed/19442259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-9-6 |
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