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Tumor induced suppression of CTL expansion and subjugation by gp96-Ig vaccination

Established tumors suppress anti-tumor immune responses and induce tolerance by incompletely characterized mechanisms, and this phenomenon is an important barrier to tumor immunotherapy. Single vaccination with tumor cells expressing gp96-Ig stimulates robust expansion of tumor-specific CTLs in tumo...

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Main Authors: Schreiber, Taylor H., Deyev, Vadim V., Rosenblatt, Joseph D., Podack, Eckhard R.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676230/
https://ncbi.nlm.nih.gov/pubmed/19223534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3706
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