HOX expression patterns identify a common signature for favorable AML

Deregulated HOX expression, by chromosomal translocations and myeloid-lymphoid leukemia (MLL) rearrangements, is causal in some types of leukemia. Using real-time reverse transcription-PCR, we examined the expression of 43 clustered HOX, polycomb, MLL and FLT3 genes in 119 newly diagnosed adult acut...

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Detalhes bibliográficos
Main Authors: Andreeff, M, Ruvolo, V, Gadgil, S, Zeng, C, Coombes, K, Chen, W, Kornblau, S, Barón, AE, Drabkin, HA
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676170/
https://ncbi.nlm.nih.gov/pubmed/18668134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.198
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