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Methylation Status of CpG Islands Flanking a CRE Motif on the Protein Phosphatase 2Acα Promoter Determines CREB Binding and Activity

Protein phosphatase 2A (PP2A) is a major serine-threonine protein phosphatase in eukaryotic cells and is involved in many essential aspects of cell function. The catalytic subunit of the enzyme (PP2Ac), a part of the core enzyme, has two isoforms, α (PP2Acα) and β (PP2Acβ), of which PP2Acα is the ma...

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Main Authors: Sunahori, Katsue, Juang, Yuang-Taung, Tsokos, George C.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676107/
https://ncbi.nlm.nih.gov/pubmed/19155497
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