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Nova-1 Mediates Glucocorticoid-induced Inhibition of Pre-mRNA Splicing of Gonadotropin-releasing Hormone Transcripts

Glucocorticoid (GC) is known to affect the reproductive system by suppressing the gonadotropin-releasing hormone (GnRH) gene expression in the hypothalamus. However, the mechanism of this effect is poorly understood. We show here that the GC-induced reduction of GnRH mRNA is due to attenuation of a...

詳細記述

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書誌詳細
主要な著者: Park, Eonyoung, Lee, Mi Sun, Baik, Sun Mi, Cho, Eun Bee, Son, Gi Hoon, Seong, Jae Young, Lee, Kun Ho, Kim, Kyungjin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676009/
https://ncbi.nlm.nih.gov/pubmed/19282286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807386200
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