Nova-1 Mediates Glucocorticoid-induced Inhibition of Pre-mRNA Splicing of Gonadotropin-releasing Hormone Transcripts

Glucocorticoid (GC) is known to affect the reproductive system by suppressing the gonadotropin-releasing hormone (GnRH) gene expression in the hypothalamus. However, the mechanism of this effect is poorly understood. We show here that the GC-induced reduction of GnRH mRNA is due to attenuation of a...

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Bibliografiske detaljer
Main Authors: Park, Eonyoung, Lee, Mi Sun, Baik, Sun Mi, Cho, Eun Bee, Son, Gi Hoon, Seong, Jae Young, Lee, Kun Ho, Kim, Kyungjin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
RNA: Processing and Catalysis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676009/
https://ncbi.nlm.nih.gov/pubmed/19282286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807386200
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