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Direct Observation of ATP-Induced Conformational Changes in Single P2X(4) Receptors

The ATP-gated P2X(4) receptor is a cation channel, which is important in various pathophysiological events. The architecture of the P2X(4) receptor in the activated state and how to change its structure in response to ATP binding are not fully understood. Here, we analyze the architecture and ATP-in...

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מידע ביבליוגרפי
Main Authors: Shinozaki, Youichi, Sumitomo, Koji, Tsuda, Makoto, Koizumi, Schuichi, Inoue, Kazuhide, Torimitsu, Keiichi
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675908/
https://ncbi.nlm.nih.gov/pubmed/19419241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000103
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