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Direct Observation of ATP-Induced Conformational Changes in Single P2X(4) Receptors
The ATP-gated P2X(4) receptor is a cation channel, which is important in various pathophysiological events. The architecture of the P2X(4) receptor in the activated state and how to change its structure in response to ATP binding are not fully understood. Here, we analyze the architecture and ATP-in...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2675908/ https://ncbi.nlm.nih.gov/pubmed/19419241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000103 |
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