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Coalescent estimates of HIV-1 generation time in vivo

The generation time of HIV Type 1 (HIV-1) in vivo has previously been estimated using a mathematical model of viral dynamics and was found to be on the order of one to two days per generation. Here, we describe a new method based on coalescence theory that allows the estimate of generation times to...

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Detalhes bibliográficos
Main Authors: Rodrigo, Allen G., Shpaer, Eugene G., Delwart, Eric L., Iversen, Astrid K. N., Gallo, Michael V., Brojatsch, Jürgen, Hirsch, Martin S., Walker, Bruce D., Mullins, James I.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26758/
https://ncbi.nlm.nih.gov/pubmed/10051616
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