Evaluation of the pharmacokinetics of digoxin in healthy subjects receiving etoricoxib

AIMS: Digoxin is a commonly prescribed cardiac glycoside with a narrow therapeutic index. The aim was to investigate whether the cyclooxygenase-2 selective nonsteroidal anti-inflammatory drug etoricoxib affects the steady-state pharmacokinetics of digoxin. METHODS: This was a double-blind, randomize...

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Hlavní autoři: Schwartz, Jules I, Agrawal, Nancy G B, Wehling, Martin, Musser, Bret J, Gumbs, Carol P, Michiels, Nicole, De Smet, Marina, Wagner, John A
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2008
Témata:
Drug Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675761/
https://ncbi.nlm.nih.gov/pubmed/18823299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03285.x
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