Evaluation of the pharmacokinetics of digoxin in healthy subjects receiving etoricoxib

AIMS: Digoxin is a commonly prescribed cardiac glycoside with a narrow therapeutic index. The aim was to investigate whether the cyclooxygenase-2 selective nonsteroidal anti-inflammatory drug etoricoxib affects the steady-state pharmacokinetics of digoxin. METHODS: This was a double-blind, randomize...

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Detalhes bibliográficos
Main Authors: Schwartz, Jules I, Agrawal, Nancy G B, Wehling, Martin, Musser, Bret J, Gumbs, Carol P, Michiels, Nicole, De Smet, Marina, Wagner, John A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Drug Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675761/
https://ncbi.nlm.nih.gov/pubmed/18823299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03285.x
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