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Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17

Sex hormones influence the susceptibility of inbred mice to liver cancer. C57BR/cdJ (BR) females are extremely susceptible to spontaneous and chemically induced liver tumors, in part due to a lack of protection against hepatocarcinogenesis normally offered by ovarian hormones. BR males are also mode...

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Autori principali: Peychal, Stephanie E.-M., Bilger, Andrea, Pitot, Henry C., Drinkwater, Norman R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675651/
https://ncbi.nlm.nih.gov/pubmed/19255062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp054
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