The 5′UTR-specific mutation in VEEV TC-83 genome has a strong effect on RNA replication and subgenomic RNA synthesis, but not on translation of the encoded proteins

Venezuelan equine encephalitis virus (VEEV) is one of the most pathogenic members of the Alphavirus genus in the Togaviridae family. Viruses in the VEEV serocomplex continuously circulate in the Central and South Americas. The only currently available attenuated strain VEEV TC-83 is being used only...

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Hauptverfasser: Kulasegaran-Shylini, Raghavendran, Thiviyanathan, Varatharasa, Gorenstein, David G, Frolov, Ilya
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675632/
https://ncbi.nlm.nih.gov/pubmed/19278709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.02.027
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