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The 5′UTR-specific mutation in VEEV TC-83 genome has a strong effect on RNA replication and subgenomic RNA synthesis, but not on translation of the encoded proteins

Venezuelan equine encephalitis virus (VEEV) is one of the most pathogenic members of the Alphavirus genus in the Togaviridae family. Viruses in the VEEV serocomplex continuously circulate in the Central and South Americas. The only currently available attenuated strain VEEV TC-83 is being used only...

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Autors principals: Kulasegaran-Shylini, Raghavendran, Thiviyanathan, Varatharasa, Gorenstein, David G, Frolov, Ilya
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675632/
https://ncbi.nlm.nih.gov/pubmed/19278709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.02.027
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