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Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging

Manganese superoxide dismutase (MnSOD or SOD2) is a key mitochondrial enzymatic antioxidant. Arguably the most striking phenotype associated with complete loss of SOD2 in flies and mice is shortened life span. To further explore the role of SOD2 in protecting animals from aging and age-associated pa...

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Main Authors: Paul, Anirban, Belton, Amy, Nag, Sanjay, Martin, Ian, Grotewiel, Michael S., Duttaroy, Atanu
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675272/
https://ncbi.nlm.nih.gov/pubmed/18078670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2007.10.013
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