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Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis

OBJECTIVE: To investigate whether single-nucleotide polymorphisms (SNPs) within the genes PRF1, GZMB, UNC13D, and Rab27a, which are involved in natural killer cell dysfunction and known to contribute to the risk of hemophagocytic lymphohistiocytosis (HLH), confer an increased risk of susceptibility...

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Hlavní autoři: Donn, Rachelle, Ellison, Stuart, Lamb, Rebecca, Day, Thomas, Baildam, Eileen, Ramanan, Athimalaipet V
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675009/
https://ncbi.nlm.nih.gov/pubmed/18311812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23270
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