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Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis

OBJECTIVE: To investigate whether single-nucleotide polymorphisms (SNPs) within the genes PRF1, GZMB, UNC13D, and Rab27a, which are involved in natural killer cell dysfunction and known to contribute to the risk of hemophagocytic lymphohistiocytosis (HLH), confer an increased risk of susceptibility...

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書誌詳細
主要な著者: Donn, Rachelle, Ellison, Stuart, Lamb, Rebecca, Day, Thomas, Baildam, Eileen, Ramanan, Athimalaipet V
フォーマット: Artigo
言語:Inglês
出版事項: Wiley Subscription Services, Inc., A Wiley Company 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675009/
https://ncbi.nlm.nih.gov/pubmed/18311812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23270
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