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The effects of membrane potential, SR Ca(2+) content and RyR responsiveness on systolic Ca(2+) alternans in rat ventricular myocytes
Previous work has shown that small depolarizing pulses produce a beat to beat alternation in the amplitude of the systolic Ca(2+) transient in ventricular myocytes. The aim of the present work was to investigate the role of changes of SR Ca(2+) content and L-type Ca(2+) current in this alternans. As...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674997/ https://ncbi.nlm.nih.gov/pubmed/19153161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.164368 |
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