Methods for Human Demographic Inference Using Haplotype Patterns From Genomewide Single-Nucleotide Polymorphism Data

We propose a novel approximate-likelihood method to fit demographic models to human genomewide single-nucleotide polymorphism (SNP) data. We divide the genome into windows of constant genetic map width and then tabulate the number of distinct haplotypes and the frequency of the most common haplotype...

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Bibliographic Details
Main Authors: Lohmueller, Kirk E., Bustamante, Carlos D., Clark, Andrew G.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2009
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674818/
https://ncbi.nlm.nih.gov/pubmed/19255370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.099275
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