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Simulating oligomerization at experimental concentrations and long timescales: A Markov state model approach

Here, we present a novel computational approach for describing the formation of oligomeric assemblies at experimental concentrations and timescales. We propose an extension to the Markovian state model approach, where one includes low concentration oligomeric states analytically. This allows simulat...

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Bibliografske podrobnosti
Main Authors: Kelley, Nicholas W., Vishal, V., Krafft, Grant A., Pande, Vijay S.
Format: Artigo
Jezik:Inglês
Izdano: American Institute of Physics 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674793/
https://ncbi.nlm.nih.gov/pubmed/19063575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3010881
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