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Mixed allele malaria vaccines: Host protection and within-host selection

Malaria parasites are frequently polymorphic at the antigenic targets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses. Conventional wisdom is therefore that vaccines directed against a single variant could select for non-target variants,...

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Detalhes bibliográficos
Main Authors: Barclay, Victoria C., Chan, Brian H.K., Anders, Robin F., Read, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674600/
https://ncbi.nlm.nih.gov/pubmed/18804509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.09.004
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