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The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi

Malaria vaccine developers are concerned that antigenic escape will erode vaccine efficacy. Evolutionary theorists have raised the possibility that some types of vaccine could also create conditions favoring the evolution of more virulent pathogens. Such evolution would put unvaccinated people at gr...

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Autori principali: Barclay, Victoria C., Sim, Derek, Chan, Brian H. K., Nell, Lucas A., Rabaa, Maia A., Bell, Andrew S., Anders, Robin F., Read, Andrew F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409122/
https://ncbi.nlm.nih.gov/pubmed/22870063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001368
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