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The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi

Malaria vaccine developers are concerned that antigenic escape will erode vaccine efficacy. Evolutionary theorists have raised the possibility that some types of vaccine could also create conditions favoring the evolution of more virulent pathogens. Such evolution would put unvaccinated people at gr...

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Detalhes bibliográficos
Main Authors: Barclay, Victoria C., Sim, Derek, Chan, Brian H. K., Nell, Lucas A., Rabaa, Maia A., Bell, Andrew S., Anders, Robin F., Read, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409122/
https://ncbi.nlm.nih.gov/pubmed/22870063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001368
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