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Raft aggregation with specific receptor recruitment is required for microglial phagocytosis of Aβ(42)
Microglial phagocytosis contributes to the maintenance of brain homeostasis. Mechanisms involved however, remain unclear. Using Aβ(42) solely as a stimulant, we provide novel insight into regulation of microglial phagocytosis by rafts. We demonstrate the existence of an Aβ(42) threshold level of 250...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674560/ https://ncbi.nlm.nih.gov/pubmed/18756527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20759 |
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