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Mutation of H63 and its catalytic affect on the methionine aminopeptidase from Escherichia coli

In order to gain insight into the mechanistic role of a flexible exterior loop near the active site, made up of Y62, H63, G64, and Y65, that has been proposed to play an important role in substrate binding and recognition in the methionyl aminopeptidase from Escherichia coli (EcMetAP-I), the H63A en...

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Detalhes bibliográficos
Main Authors: Mitra, Sanghamitra, Bennett, Brian, Holz, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674292/
https://ncbi.nlm.nih.gov/pubmed/18952013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.09.012
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