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Analyzing the binding of Co(II)-specific inhibitors to the methionyl aminopeptidases from Escherichia coli and Pyrococcus furiosus

Methionine aminopeptidases (MetAPs) represent a unique class of protease that is capable of the hydrolytic removal of an N-terminal methionine residue from nascent polypeptide chains. MetAPs are physiologically important enzymes; hence, there is considerable interest in developing inhibitors that ca...

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Autors principals: Mitra, Sanghamitra, Sheppard, George, Wang, Jieyi, Bennett, Brian, Holz, Richard C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678238/
https://ncbi.nlm.nih.gov/pubmed/19198897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-009-0471-2
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