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Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells

It is important to understand the regulation of stem cell division because defects in this process can cause altered tissue homeostasis or cancer. The cyclin-dependent kinase inhibitor Dacapo (Dap), a p21/p27 homolog, acts downstream of the microRNA (miRNA) pathway to regulate the cell cycle in Dros...

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Detalhes bibliográficos
Main Authors: Yu, Jenn-Yah, Reynolds, Steven H., Hatfield, Steve D., Shcherbata, Halyna R., Fischer, Karin A., Ward, Ellen J., Long, Dang, Ding, Ye, Ruohola-Baker, Hannele
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674257/
https://ncbi.nlm.nih.gov/pubmed/19336466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.025999
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