Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to the heterotypic neutralization domain of VP7 and the VP8 fragment of VP4.

A murine model was used to determine whether neutralizing monoclonal antibodies (MAbs) with heterotypic specificity directed to VP7 (MAb 57-8) or to the VP8 fragment of VP4 (MAb M14) passively protect mice against challenge with various strains of rotavirus. (The gene 4 product, an outer capsid prot...

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Detalhes bibliográficos

Publicado no:	J Clin Microbiol
Principais autores:	Matsui, S M, Offit, P A, Vo, P T, Mackow, E R, Benfield, D A, Shaw, R D, Padilla-Noriega, L, Greenberg, H B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC267419/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2470774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.27.4.780-782.1989
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