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Altering PPARγ Ligand Selectivity Impairs Adipogenesis by Thiazolidinediones But Not Hormonal Inducers

Peroxisome proliferator–activated receptor γ (PPARγ) acts as a ligand-dependent transcription factor with a key role in mediating adipocyte differentiation and insulin sensitivity. Recently, we and others have shown that PPARγ recruits the nuclear corepressors NCoR and silencing mediator for retinoi...

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Hlavní autoři: Samarasinghe, Shanika P., Sutanto, Maria M., Danos, Arpad M., Johnson, Daniel N., Brady, Matthew J., Cohen, Ronald N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674133/
https://ncbi.nlm.nih.gov/pubmed/19165156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2008.629
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