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The Isolated Sixth Gelsolin-Repeat and Headpiece Domain of Villin Bundle F-actin in the Presence of Calcium and are Linked by a 40-Residue Unstructured Sequence ,

Villin is an F-actin regulating, modular protein with a gelsolin-like core and a distinct C-terminal ‘headpiece’ domain. Localized in the microvilli of the absorptive epithelium, villin can bundle F-actin and, at higher calcium concentration, is capable of a gelsolin-like F-actin severing. The headp...

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Autors principals: Smirnov, Serge L., Isern, Nancy G., Jiang, Zhenghui G., Hoyt, David W., McKnight, C. James
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674016/
https://ncbi.nlm.nih.gov/pubmed/17547371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700110v
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