Phase II Studies of Gemcitabine and Cisplatin in Heavily and Minimally Pretreated Metastatic Breast Cancer

PURPOSE: Cisplatin and gemcitabine have single-agent activity in metastatic breast cancer, and preclinical data support synergy of the combination. Two parallel, phase II trials were conducted to evaluate the response rate, response duration, and toxicities of the combination. Genetic polymorphisms...

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Dettagli Bibliografici
Autori principali: Chew, Helen K., Doroshow, James H., Frankel, Paul, Margolin, Kim A., Somlo, George, Lenz, Heinz-Josef, Gordon, Michael, Zhang, Wu, Yang, Dongyun, Russell, Christy, Spicer, Darcy, Synold, Tim, Bayer, Robert, Hantel, Alexander, Stiff, Patrick J., Tetef, Merry L., Gandara, David R., Albain, Kathy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2009
Soggetti:
Original Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674003/
https://ncbi.nlm.nih.gov/pubmed/19307510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.4839
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